Simply put, "the biggest family of misfits, outcasts and badasses," as quoted by their leader, Big Mitch Baker. A group of stereotypical bikers, they wear leather, give off a gruff, tough persona, have long beards and hair, wear biker attire and ride chopper style motorcycles. Circa 1986, they are the only gang, along with the Cuban Gang, that Tommy Vercetti opens relations without forcibly taking it over. The Hells Angels biker gang is a likely inspiration of the gang, as there were later seen to be hired as security for a concert of the hair metal band Love Fist. This is an obvious reference to The Rolling Stones' show at Altamont, where Hells Angels were hired as security and an Angel stabbed a member of the crowd. They are heavily influenced by German Culture, for some of them have EisernKruez (Iron Cross) tattoos on their shoulders, as well as wearing Pickelhaubes.
In Vice City Stories the Biker Gang are revealed to be a large gang owning several businesses across Vice City. It is assumed that due to Victor Vance's takeovers that the once large gang is reduced to only the Greasy Chopper Bar Downtown by GTA: Vice City.