Michael Keane, also known as Saint Michael, was a member of the McReary Mob. He was often called stupid by Packie McReary and the others, and was often accused of being inbred. Although he never directly confirmed the accusation, he never denied it either. He often worked with McReary and Gordon Sargent, specializing in robberies and hijackings.
Keane accompanied McReary, Sargent and Niko Bellic to an Ancelotti waste management plant at Colony Island, shooting their way in and successfully stealing the Ancelottis' payment. Keane and Sargent provided covering fire as McReary and Bellic made their escape.
Soon after, Keane took part in a bank robbery at the Bank of Liberty in Chinatown, Algonquin, along with Packie, Derrick and Niko; but one of the hostages, Eugene Reaper, shot and killed him with a concealed gun, much to the distress of Packie who, along with Derrick, avenged Keane's death by immediately killing Reaper. After the three surviving members had escaped in a car, Packie wished he had been nicer to Michael.