|Appearances||The Ballad of Gay Tony|
|Full Name||Vincenzo Pelosi|
|Date of Death||2008|
|Family||Rocco Pelosi (Nephew)|
Luis Fernando Lopez
|Voiced by||John Tormey|
Vincenzo Pelosi also known as Vince, was a 60-year old Ancelotti enforcer who often worked with his nephew Rocco Pelosi. He and Rocco told Luis to kill Tony, but when Luis was about to and he apologized to Tony, Luis shot Vince in the head to threaten Rocco. Rocco was free to go because he was a made man, and hitmen would attack Luis if he killed Rocco. It is stated by Tony Prince that Vince and his nephew Rocco are related to Gracie Ancelotti (possibly on her mother's side).
Vincenzo was voiced by John Tormey.
- It is likely his last name is Pelosi as he is Rocco Pelosi's uncle.
- Uncle Vince may be a subtle throwback to Grand Theft Auto III character Ray Machowski, bearing a slight physical similarity, as well as sharing the same meeting place (Ray gives out missions from the underground restrooms in Belleville Park, the GTA III version of Central Park, whereas Vince is met alongside Rocco in Middle Park, GTA IV's version of Central Park, also in the underground restrooms).
- Uncle Vince refers to Luis Fernando Lopez as being Mexican.
- The Ballad of Gay Tony