The Vice Squad are an elite branch of the Vice City Police Department. They appear, and begin to chase, the player upon reaching a three-star wanted level. The Vice Squad members come in pairs and drive VCPD Cheetahs of varying colours which are fast and can easilly catch up with the player on foot or in a car. The VCPD Cheetah is the only emergency vehicle that can be resprayed in a Pay 'n' Spray and/or a Spray 'n' Go. The Vice Squad members carry Micro-SMGs which can make short work of the player. Killing a Vice Squad member will cause them to drop their Micro SMG as well as two wads of cash. The Vice Squad members are the only law enforcement members who drop money upon being killed. These Vice City Vice Squad members always arrive as two unaided officers, dressed casually, but tastefully. The Vice Squad are based in the Little Havana Police Station. A VCPD Cheetah spawns at the back of the station.
The Vice Squad members are meant to emulate Sonny Crockett and Ricardo Tubbs from 80's television's series and 2006 film Miami Vice, a drama focusing on well-dressed, seemingly overpaid vice officers in Miami, who drive expensive sports cars and live a life of luxury and adventure. They are slightly more dangerous than other officers, but they can still be killed easily otherwise.