The Vinewood Tour is a pastime available in GTA V. At certain times of the day, the Vinewood Tour bus will be parked next to the Wax Museum on Vinewood Boulevard and a bus icon will appear. For a fee of $40, the character can take a tour (lasting approximately 15 minutes of real time) past a number of landmarks in the vicinity (including several homes of the stars in Vinewood Hills), as a female tour guide talks about the area's sordid history (most of her anecdotes involve sexual or drug misadventures).
About a dozen locations are featured in the tour, and the player can choose to skip to the next one or allow the bus to drive between each location. During the drive between locations, the tour guide and passengers will make random remarks about Vinewood.
One stop of note is Vinewood's Epsilon headquarters, and the tour guide will reveal she is a member.
During the tour, the player can toggle between first-person or third person view; in third-person view the camera will automatically focus on highlighted locations; the first-person view offers only limited visibility due to the character sitting behind a wall of the bus. The tour ends at the same location from which it starts.
Completing the bus tour does not appear to be necessary for 100% completion.
Due to its length, generally starting the tour during daylight hours means much of the tour will take place after dark. Taking the tour, while not necessarily valuable from a "lay of the land" perspective, is a good way to enjoy the game universe and AI design while letting someone else drive in a non-mission setting.