Debonaire is a brand of cigarette advertised in the HD Universe. They can be seen advertised on billboards in Liberty City, and Southern San Andreas and are also sold on the in-game website, Yourmexicandoctor.com. The player cannot purchase Debonaire cigarettes in GTA IV, however the player can purchase company stock in GTA V.
- Debonaires appear to be regarded as a very "feminine" cigarette, as seen on the Redwoods website, which states that "no real man would smoke a Debonaire, even if he was drunk". This is ironic as the word 'debonaire' is an adjective used for describing a refined and sleek man.