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|Game||The Lost and Damned|
|Target||The Angels of Death Bikers|
|Unlocked by||Angels in America|
This opening cutscene shows Billy Grey talking to a Dave Grossman, a member who is also a lawyer for Goldberg, Ligner and Shyster. Billy casually offers Dave a bong hit, which he spiked with mescaline causing Grossman to go on a high that Billy says he "could be trippin for days". Johnny enters and has to talk to Billy, telling Dave to "fuck off" so he can speak privately with Billy. While conversing about the club's business and their relationship, Billy receives a text message informing him that members of The Lost were attacked by AOD members.
- If Johnny abandons his bike,he will get a ride back to the clubhouse by Billy,and he will fail the mission.
- It is possible to save the bikers engaged in the shootout, it is hard, due to them being under heavy fire from AoD members, and having health like a normal pedestrian. The player needs heavy weapons like the M4/AK-47 to kill the AoD members fast enough to make sure they can escape to their bikes and drive off.
- News reports of the GTA IV mission "Roman's Sorrow" will appear on the internet and radio after this mission. This is to move the story along faster as TLAD moves to Bohan after It's War, bringing it in line with Niko's story. As noted above, the events of No Love Lost take place either current with or shortly before this mission.
- When outside of the Angles of Death clubhouse, if you look behind the two vans, you can see custom flame decal bikes. These can be saved if the player drives away with the bike and parks it in the safe zone, then goes back and shoots a Lost member to fail the mission.