Events concerning the Grand Theft Auto series in 1949.
- February 8: George Cheung, who voices Wei Cheng in Grand Theft Auto V, is born in Hong Kong.
- March 25: Tuck Milligan, who voices Barry in GTA V, is born in Kansas City, Missouri.
- April 18: John Braden, who voices Miles O'Donovan in Grand Theft Auto: Liberty City Stories, is born in Little Rock, Arkansas.
- May 26: Pam Grier, who voices herself in GTA V, is born in Winston-Salem, North Carolina.
- May 26: Philip Michael Thomas, who voiced Lance Vance in Grand Theft Auto: Vice City and Grand Theft Auto: Vice City Stories, is born in Columbus, Ohio.
- December 6: Maureen Silliman, who voices Jan Brown in GTA Vice City, is born in New York City, New York.
- 2D Universe
- HD Universe
- July 20: An unnamed person dies and is buried at the Hill Valley Church in Pacific Bluffs, Los Santos.
- Alfonso Vasquez is born in Mexico City, Mexico.
- Fred Quincy murders Isaac and his secretary. He writes a confession letter to David Richards on August 14th.
- Jon Gravelli is arrested for bribery.
- The Angels of Death are founded in San Andreas.
- The Suds Law Laundromat at the corner of Macdonald St and Strawberry Ave in Davis, Los Santos is opened.
- The Los Santos Panic baseball team win the league championship.