A hi-lo game in progress at the Lost MC clubhouse.

Hi-Lo is a card game that is featured in The Lost and Damned. Johnny can play the game against other members of the Lost MC on the second floor of the clubhouse.

The basic objective of the game is to guess whether the next card dealt will be of a higher or lower value than the current card on the table. Each player takes it in turn to guess. If their guess is correct, they stay in the game and the next player along the table takes their turn. If a player guesses incorrectly, they are removed from the game until the next round. The last player left after all others have guessed incorrectly and thus been excluded is the winner, and takes the pot - $40.

It should be noted that in this game, Aces are low. Also, if the next card dealt is the same value as the card currently on the table, then the game counts the guess as incorrect.

After the completion of the final mission, Get Lost, Johnny can no longer play Hi-Lo.